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Saturday, December 14, 2019

A patent dispute means that the marketing of a biosimilar for patients with inflammatory bowel disease will be delayed, despite approval by the US Food and Drug Administration, investigators report. Medscape Medical News

Brolucizumab Gets EU Panel Backing for Wet AMD

Saturday, December 14, 2019

The treatment, previously approved by the FDA, offers less-frequent injections, and efficacy proven in two head-to-head global trials. International Approvals

FDA Approves New Interoperable Insulin Dosing 'Controller'

Saturday, December 14, 2019

The Tandem Diabetes Care Control-IQ Technology is the first to allow communication between interoperable pumps and continuous glucose monitors, representing a step forward in closed-loop technology. FDA Approvals

FDA Approves Amarin's Vascepa for CV Risk Reduction

Friday, December 13, 2019

The purified, high-dose form of eicosapentaenoic acid was approved for elevated triglycerides as an add-on to high-dose statins, following a unanimously positive advisory-panel recommendation. FDA Approvals

EXCEL Leaders Answer Back After BBC Exposé

Friday, December 13, 2019

Reaction to claims of study misconduct have dominated the press and social media since the report dropped earlier this week. Medscape Medical News

Paclitaxel Pill Tops IV Response, but Needs 9-Hour Fast

Friday, December 13, 2019

Among women with metastatic breast cancer, use of an investigational oral form of paclitaxel yielded a higher overall response rate than the IV form, but administration was unique and time-consuming. Medscape Medical News

'Remarkable' New Data on Menopausal Hormone Therapy

Friday, December 13, 2019

Estrogen alone and estrogen/progestin have opposite effects on breast cancer risk; adding progestin may lead to a lifetime of increased risk. Medscape Medical News

Inpatient Rehabilitation Facility Quality Measure Flawed

Friday, December 13, 2019

Readmission within 30 days failed to distinguish between high- and low-performing inpatient rehabilitation facilities, a study found. Medscape Medical News

Company-Reported, Guideline Author Disclosures Often at Odds

Friday, December 13, 2019

One might expect general agreement between industry-reported numbers and author disclosures of payments, but that apparently didn't happen for writing committee members of nine recent ACC/AHA guidelines. Medscape Medical News

Negative Phase 2 Trial Data Ends Development of PSP Drug

Friday, December 13, 2019

Phase 2 trial results show gosuranemab did not meet primary or key secondary endpoints in patients with progressive supranuclear palsy, leading to discontinuation of the drug's development for PSP. Medscape Medical News

FDA OKs Golodirsen (Vyondys 53) for Duchenne Muscular Dystrophy

Friday, December 13, 2019

Golodirsen is the first treatment for Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation amenable to exon 53 skipping. FDA Approvals

Jury Still Out on Whether to Treat Subclinical Hypothyroidism in Elderly

Friday, December 13, 2019

A new systematic review suggests elderly patients with overt hypothyroidism should receive levothyroxine treatment, but for those with subclinical hypothyroidism, the advice is less certain. Medscape Medical News

Collagen: 'Fountain of Youth' or Edible Hoax?

Friday, December 13, 2019

Used by Chinese women for centuries to maintain youthful appearance, the collagen supplement market in the United States is expected to reach $293 million in 2020. Some clinicians remain skeptical. WebMD Health News

Breakfast Like a King: Three-Meal Diet Improves Type 2 Diabetes

Friday, December 13, 2019

A three-meal diet plan improves glycemic endpoints and leads to weight loss and less insulin use in type 2 diabetes compared with the usual diabetic diet of six small meals a day. Medscape Medical News

ImmunoRx in TNBC: Conflicting Results

Friday, December 13, 2019

Two separate studies reach very different endpoints with addition of immunotherapy in triple-negative breast cancer. Researchers are now asking why. Medscape Medical News

Senate Confirms Stephen Hahn as New FDA Chief

Thursday, December 12, 2019

Dr. Stephen Hahn was on Thursday confirmed as the new head of the U.S. Food and Drug Administration, taking charge at a regulatory agency that oversees products ranging from complex cancer drugs, to food, cosmetics and tobacco. Reuters Health In...

Scientists Home in on Potential Treatments for Deadly Nipah Virus

Saturday, December 14, 2019

Scientists working on how to combat a highly infectious and deadly virus called Nipah, which is transmitted to humans from bats and pigs, say they have found around a dozen potential drugs that might be developed to block the disease. Reuters He...

Ten-Year Results Support Partial Breast Irradiation

Thursday, December 12, 2019

A current phase 3 trial showed that partial breast irradiation — as opposed to irradiating the whole breast — could be a viable alternative in patients with early, low-risk breast cancer. Medscape Medical News

Clinicians Can Be That 'One Caring Adult' Who Changes a Life

Thursday, December 12, 2019

Parents, teachers, and coaches are often thought of as the people who make a difference in the lives of young people, but even a single interaction can inspire, reports former foster child Josh Shipp. Medscape Medical News

Abortion Reversal Study Stopped Early for Severe Bleeding

Thursday, December 12, 2019

Several state laws mandate that healthcare providers tell women a medical abortion can be "reversed" using a procedure that is unproven and may be dangerous for the women. Medscape Medical News